Sinai-Grace Hospital (SGH) Outpatient Anticoagulation Clinic

Phone: (313) 592-3535

Fax: (313) 592-3538  

Patient appointment hours:

Monday, Tuesday, and Friday: 8:30 – 11:50 AM

Wednesday and Thursday: 1:40 PM – 4:00 PM                          

Referral Process for Enrollment of patients:

Consult Information:

·         Consults may be made by Internal Medicine Residents and/or associated precepting physicians

·         The patient MUST be an active Internal Medicine Resident clinic patient (Primary Care Clinic)

·         An enrollment form must be fully completed and signed by the resident who will serve as the primary care physician responsible for the patient’s anticoagulation therapy.

·         Enrollment forms can be obtained by emailing skarr@dmc.org, by stopping by the Anticoagulation Clinic office (clinic room 286), or by contacting the SGH Anticoagulation Service at (313) 592-3535.

·         Requests for enrollment forms and consult information may be left on the voicemail for (313) 592-3535; however, no patient will be accepted into the SGH Anticoagulation Clinic until a completed referral form has been received and the patient case reviewed by the clinic pharmacist.

·         The completed and signed enrollment form may be hand delivered to the Anticoagulation Clinic office, or faxed to: 313-592-3538.  If faxed, a call should be placed to ensure that the fax was received.

·         Consults are not accepted on a “STAT” basis.  Patients are seen by appointment only.

·         Once a consult has been reviewed and the patient accepted for enrollment into the SGH Anticoagulation Clinic, the Internal Medicine resident will be notified by numeric or text page.

·         Until notification is received that the SGH Anticoagulation Clinic will begin monitoring a patient, the resident is responsible for managing anticoagulation, including evaluating PT/INR results, making warfarin dose adjustments, continuing or discontinuing low molecular weight heparin (Lovenox or Fragmin) and scheduling return lab draws via venipuncture phlebotomy.

·         Consults will be in effect for a total of 3-6 months (see discharge information on back of page)

Criteria for Acceptance of Patients into the Sinai-Grace Outpatient Anticoagulation Clinic:

·         The patient must be an established clinic patient in the Primary Care Clinic

·         The patient must:

o        Be at least 18 years of age

o        Provide contact information (primary and secondary telephone numbers and home address)

o        Can be reached by telephone and has adequate transportation to/from the clinic

o        Not involved in any active substance abuse

·         The patient must have an indication for warfarin that is consistent with guidelines published in The Seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy: Evidence-Based Guidelines, 2004, or consistent with usual medical practice (benefit of anticoagulation outweighs the risk)

·         The referring resident must have a plan in place to adequately manage warfarin until the first SGH Anticoagulation Clinic visit is scheduled (usually within 7 days from referral date)

·         The physician agrees for the clinic pharmacist to independently manage anticoagulation with warfarin and/or low molecular weight heparin (LMWH) or fondaparinux within clinic guidelines, including prescribing for these medications in the physician’s name

·         The physician agrees to be notified as per clinic protocol (INR >6.0, other unusual situations)

·         The patient is agreeable to having their anticoagulation managed by the clinic pharmacist

·         The patient must see his/her physician at least every six months (or more often—as instructed by the resident)


Additionally, patients will be discharged from the SGH Anticoagulation Clinic Service if the patient: 

·         is no longer receiving warfarin

·         repeatedly fails to come in for INR visits--three no call, no shows without extenuating circumstances.  In this instance, a letter will be sent to the physician and the patient to notify him/her that they have been discharged from the clinic. 

·         otherwise misses several clinic appointments to warrant unsafe practice

·         decides to transition their care to another physician outside of the Primary Care Clinic

·         the patient changes or disconnect phone numbers or moves without notifying the SGH Anticoagulation Clinic and has missed appointments as a result

·         is noted to be an active substance abuser without attempting rehabilitation

·         behaves in a hostile or violent manner toward staff or is unwilling to following instructions

·         has a primary care physician who wishes to manage the anticoagulation themselves

·         has a primary care physician who repeatedly adjusts warfarin or low molecular weight anticoagulation after SGH Anticoagulation Clinic enrollment without notifying the clinic pharmacist

·         has stable (therapeutic) INR results for >2 months, the patient may be referred back to their primary care resident* for anticoagulation management in order to allow room in the clinic for new, unstable patients

·         has been managed in the Anticoagulation Clinic for a total of six or more months, despite sub- or supra-therapeutic INR results.  The patient will then be referred back to their primary care resident* for anticoagulation

How to transition anticoagulation and enroll in the Anticoagulation Clinic:

Transitioning Anticoagulation from Inpatient:

1.       Order baseline labs (PT/INR, hepatic function and renal function) prior to starting warfarin and/or LMWH

2.       If INR is therapeutic, add up total warfarin doses in mg and divide by the number of warfarin days for approximate daily dose and subsequent weekly dosing regimen.

example: day 1 = 5 mg, day 2 = 6 mg, day 3 = 5 mg, day 4 = 7.5 mg; total is 23.5 mg/4 days = 5.9 mg per day.  Give patient Rx for 6 mg, #30, take one daily or as directed by doctor (do not give too many tablets or refills)

3.       If INR is NOT therapeutic prior to discharge, look at warfarin doses for previous days and INR trend to determine warfarin daily dose for next several days.  In general, starting doses are:

a.       2.5 mg daily: patients with impaired hepatic function, wt <45 kg or females over age 65

b.       5 mg daily: usual starting dose for most patients and males over 65

c.       7.5 mg daily: may be considered for age <35, weight at least 70 kg with normal hepatic function. 

d.       If patient on antibiotic or other interacting drug at discharge, consult with hospital/clinic pharmacist

4.       Prior to discharge, instruct patient to follow-up in Primary Care Clinic:

a.       Within 3-4 days for therapeutic INR

b.       Within 2-3 days for subtherapeutic or supratherapeutic INR

5.       Give patient primary care clinic telephone number on discharge paperwork (313-592-3680) and remind them that they need to schedule a follow-up with you immediately as described above

6.       After 1st clinic visit with patient post-discharge, you may refer them to the SGH Anticoagulation Clinic.  Complete SGH Anticoagulation referral form, fax to (313) 592-3538 and call (313-592-3535) to confirm receipt.  No referrals will be accepted from the hospital on discharge—the patient must be seen in the clinic first

7.       Go under “Patient List” in CIS and under “modify list” choose list on the left titled, “Patients referred to SG Anticoagulation Clinic.”  Move this over to your active lists on the right.  You can now view all patients referred and add this new patient to the list of referred patients so that you don’t lose track of them. 

8.       Expect notification of patient acceptance for anticoagulation management within a few business days of sending the referral.  Clinic pharmacist will then contact patient to set up an initial appointment with the SGH Anticoagulation Clinic and take the patient off of the “Patients referred to SG Anticoagulation Clinic” list in CIS.

Adjusting warfarin in the outpatient setting:

1.       If patient on warfarin for <1 week follow steps 2-4 above

2.       If patient already on warfarin for >1 week, follow dosing algorithms (see separate pages)

3.       Complete SGH Anticoagulation referral form as in #6 above